Medium-term outcomes after laparoscopic revision of laparoscopic Kasai portoenterostomy in patients with biliary atresia

نویسندگان

چکیده

Abstract Objective To determine whether revision laparoscopic Kasai portoenterostomy (RLKPE) is a viable treatment option for patients with biliary atresia (BA) who had undergone initially successful (ILKPE). Methods The medical records of 312 nonsyndromic BA ILKPE between May 2009 and 2017 were retrospectively reviewed. divided into three groups according to their outcomes after ILKPE: group A: 25 RLKPE; B: 203 required no further surgical intervention; C: 84 failed either died or liver transplantation survival. 3-year 5-year survival native (SNL) rates compared A B C. Among the in A, perioperative data RLKPE those ILKPE. Results Of ILKPE, 228 reached normal bilirubin concentration range within 6 months postoperatively. them, sudden cessation bile flow RLKPE. Adequate drainage, as evidenced by normalized conjugated levels, was achieved 80% variables, including operative time, blood loss, rate conversion open surgery complications RLKPE, not significantly different SNL 64.0% 52.0%, respectively, which from corresponding 86.2% 73.9%, unrevised ( P > 0.05). Conclusion Our demonstrated that RPLKE effective drainage can delay need transplantation, yielding encouraging medium-term patient outcomes.

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ژورنال

عنوان ژورنال: Orphanet Journal of Rare Diseases

سال: 2021

ISSN: ['1750-1172']

DOI: https://doi.org/10.1186/s13023-021-01835-z